SnapShot: Mechanosensing Matrix

نویسندگان

  • Jerome Irianto
  • Charlotte R. Pfeifer
  • Yuntao Xia
  • Dennis E. Discher
چکیده

Cells sense and respond to properties of their microenvironment that can affect cell morphology, protein levels and localization, gene expression, and even nuclear integrity. Tissue micro-stiffness, largely influenced by extracellular matrix, varies dramatically within an organism and can be a useful parameter to both clarify and organize a wide range of cell and molecular processes, such as genomic changes in cancer.

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عنوان ژورنال:
  • Cell

دوره 165  شماره 

صفحات  -

تاریخ انتشار 2016